How to download small RNA-Seq data and find adaptors de novo For someone not experienced in bioinformatics, it is not clear how to search for small RNA-Seq data sets and what are the best methods for downloading them. Unfortunately, downloading the data is only the beginning of the battle. Often times it isn't possible to find information about the 3' adaptor sequence, which is needed for trimming this sequence off of the reads. This file will read a fastq file and print out the most abundant k-mers beginning from the 5' end of the read. To learn how to find and download small RNA-Seq data and how to utilize this code, check out the video below or here.